Steroid Hormones Therapies in an Aging Society: Supplement. Anti-apoptotic Effect of Dehydroepiandrosterone and Its Role in an Aging Society
Year: 2004
Type: article
Abstract: 50 mg DHEA was orally administered for 2 weeks.DHEA (25 mg or 50 mg) administration for 1 week or 2 weeks resulted in several fold increase in the serum concentrations of DHEA, DHEA-S and estradiol, while the same treatment did not result in a significant increase in that of testosterone.In addition.somatomedin C, a possible cause of somatopause with aging was slightly increased by 50 mg DHEA administration, suggesting that DHEA may also be effective in the improvement of somatopause (Fig. 2).No significant side effects were observed in respect to symptoms and blood chemistry.Based on these data, we are now planning a long-term trial of DHEA replacement in normal elderly individuals.
Source: Internal Medicine
Institution: Yokohama City University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2172978234