Work

A review of methods for subtyping Yersinia pestis: From phenotypes to whole genome sequencing

Year: 2015

Type: review

Abstract: Numerous subtyping methods have been applied to Yersinia pestis with varying success. Here, we review the various subtyping methods that have been applied to Y. pestis and their capacity for answering questions regarding the population genetics, phylogeography, and molecular epidemiology of this important human pathogen. Methods are evaluated in terms of expense, difficulty, transferability among laboratories, discriminatory power, usefulness for different study questions, and current applicability in light of the advent of whole genome sequencing.

Source: Infection Genetics and Evolution

DOI: 10.1016/j.meegid.2015.10.024

Authors: Amy J. Vogler, Paul Keim, David M. Wagner

Institutions: Northern Arizona University, Translational Genomics Research Institute

Language: English

Topic: Yersinia bacterium, plague, ectoparasites research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $2,730

Funders: U.S. Department of Homeland Security, Northern Arizona University, Science and Technology Directorate