Year: 2015
Type: review
Abstract: Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have identified immune biomarkers able to predict a protective humoral immune response to the vaccine. In this review, we summarize current knowledge on the effects of aging on influenza vaccine responses and on biomarkers so far identified, and we discuss the relevance of latent cytomegalovirus (CMV) infection on these vaccine responses.
Authors: Daniela Frasca, Bonnie B. Blomberg
Institution: University of Miami
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: Regulation of B Lymphocyte Defects in Senescent Humans, Regulation of Immunoglobulin Class Switch in Aged Mice, Molecular mechanisms for TNF-mediated inhibition of B lymphocyte function, Regulation of primary and memory B cell vaccine responses in the elderly, G9000052191, Micro-RNAs: a new mechanism negatively regulating B cell responses in the elderly
OpenAlex ID: W2174825619