Work

Bacteriophage-induced Mutation in Escherichia Coli

Year: 1963

Type: article

Abstract: A new temperate bacteriophage (phage Mul) of E. coli strain K12 is described. Sensitive bacteria infected with Mu1 exhibit increased forward mutation rates at many gene loci. The prophage of Mul is always closely linked to the chromosomal sites of phage-induced mutation It is proposed that loss of genetic functions is a direct consequence of phage integration at functional loci. The potential uses of this system for studying the mechanism of integration are discussed. (auth)

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.50.6.1043

Author: Austin L. Taylor

Institution: Brookhaven National Laboratory

Language: English

Topic: Bacteriophages and microbial interactions

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2175531321

FWCI: 3.905

Cites: 21

Cited by: 372

Related to: 10