Cerebral Small Vessel Disease in Dementia and Depression: a prospective population-based MRI study
Year: 2004
Type: dissertation
Study design: Observational Study
Abstract: __Abstract__ \n \nCerebral white matter lesions and asymptomatic brain infarcts are common in elderly \npeople. These brain lesions are thought to result from cerebral small vessel disease, \nand their presence and severity increase with age and the presence of arterial \nhypertension. There is widespread belief that cerebral small vessel disease plays a role in \nthe aetiology of dementia. Small vessel disease is commonly regarded as the primary pathology \nin subcortical ischemic vascular dementia, one of the subtypes of vascular dementia. \nFurthermore, vascular factors, including cerebral small vessel disease, are increasingly \nrecognized to be involved in the aetiology of Alzheimer’s disease.8 However, there is hardly \nany evidence from prospective population-based studies to support these notions.
Author: Niels D. Prins
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2176402619