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Performance of the Cryptococcal Antigen Lateral Flow Assay in Non-HIV-Related Cryptococcosis

Year: 2015

Type: article

Abstract: The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.02223-15

Authors: Anupop Jitmuang, Anil A. Panackal, Peter R. Williamson, John E. Bennett, John P. Dekker, Adrian M. Zelazny