Work

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Year: 2011

Type: article

Source: Nature

DOI: 10.1038/nature10602

Authors: Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell, Katherine R. Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M. Jewell, Zachary R. Johnson, Darrell J. Irvine, Leonard Guarente, Joanne K. Kelleher, Matthew G. Vander Heiden, Othon Iliopoulos, Gregory Stephanopoulos

Institutions: Massachusetts Institute of Technology, Massachusetts General Hospital, University of Coimbra, Howard Hughes Medical Institute, Dana-Farber Cancer Institute

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, Damon Runyon Cancer Research Foundation, Wellcome Trust, Agios Pharmaceuticals, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Hypoxia-induced Metabolic Changes in Cancer, Elucidating modulators of hepatic metabolism by quantitative flux analysis, Identification of Biomarkers for Early Detection of Renal Cell Carcinoma, Cancer Center Support (Core) Grant

OpenAlex ID: W2116516144

FWCI: 32.08

Cites: 43

Cited by: 1,777

Related to: 10