Work

Comprehensive analytical model for CW laser induced heat in turbid media

Year: 2015

Type: article

Abstract: In this work, we present a new analytical approach to model continuous wave laser induced temperature in highly homogeneous turbid media. First, the diffusion equation is used to model light transport and a comprehensive solution is derived analytically by obtaining a special Greens' function. Next, the time-dependent bio-heat equation is used to describe the induced heat increase and propagation within the medium. The bio-heat equation is solved analytically utilizing the separation of variables technique. Our theoretical model is successfully validated using numerical simulations and experimental studies with agarose phantoms and ex-vivo chicken breast samples. The encouraging results show that our method can be implemented as a simulation tool to determine important laser parameters that govern the magnitude of temperature rise within homogenous biological tissue or organs.

Source: Optics Express

DOI: 10.1364/oe.23.031069

Authors: Hakan Erkol, Farouk Nouizi, Alex Luk, Mehmet Burcin Unlu, Gultekin Gulsen

Institutions: University of California, Irvine, Boğaziçi University

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,270