Kinesin spindle protein (KSP) inhibitors. Part 3: Synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility
Year: 2006
Type: article
Authors: Robert M. Garbaccio, Mark E. Fraley, Edward S. Tasber, Christy M. Olson, William F. Hoffman, Kenneth L. Arrington, Maricel Torrent, Carolyn A. Buser, Eileen S. Walsh, Kelly Hamilton, Michael D. Schaber, Christine Fernandes, Robert B. Lobell, Weikang Tao, Vicki J. South, Youwei Yan, Lawrence C. Kuo, Thomayant Prueksaritanont, Donald E. Slaughter, Cathy Shu, David C. Heimbrook, Nancy E. Kohl, Hans E. Huber, George D. Hartman
Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: closed
OpenAlex ID: W2177687085