Year: 2013
Type: article
Abstract: Today, depression is one of the most important health problems. Despite the progress made in the treatment of depression, treatment resistance and chronicity still remains a major problem. New research and the new treatments on the etiology and treatment of depression are directed from “genetic versus environmental roles to genetic-environmental interactions”, from “chemical imbalance to inflammatory processes”, from “neurotransmitters to neuroplasticity and neurotrophic factors”, from “serotonin, norepinephrine and dopamine to glutamate”, from “pills to intravenous infusions”, from “monotherapy to augmentation strategies”, from “pharmacotherapy to neuromodulation”. In the treatment of treatment-resistant unipolar depression (TRUD) “switch to another drug from the same group, choosing a drug from different groups, add another drug to available drug, electroconvulsive therapy” as is known methods beside recently “repetitive transmagnetic stimulation (rTMS), deep brain stimulation (DBS), vagal nerve stimulation (VNS)” such non-pharmacological treatments have been accepted and the use of them has become common.
Source: DergiPark (Istanbul University)
Author: Servet Ebrinç
Language: Turkish
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2177815812