Work

Neurotrophic Factors and Their Potential Applications in Tissue Regeneration

Year: 2015

Type: review

Abstract: Neurotrophic factors are growth factors that can nourish neurons and promote neuron survival and regeneration. They have been studied as potential drug candidates for treating neurodegenerative diseases. Since their identification, there are more and more evidences to indicate that neurotrophic factors are also expressed in non-neuronal tissues and regulate the survival, anti-inflammation, proliferation and differentiation in these tissues. This mini review summarizes the characteristics of the neurotrophic factors and their potential clinical applications in the regeneration of neuronal and non-neuronal tissues.

Source: Archivum Immunologiae et Therapiae Experimentalis

DOI: 10.1007/s00005-015-0376-4

Authors: Nan Xiao, Quynh-Thu Le

Institutions: University of the Pacific, Stanford Medicine, Stanford University

Language: English

Topic: Nerve injury and regeneration

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Dental and Craniofacial Research