Work

A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models in R

Year: 2015
Type: article
Abstract: This tutorial presents the application of an R package, RxODE, that facilitates quick, efficient simulations of ordinary differential equation models completely within R. Its application is illustrated through simulation of design decision effects on an adaptive dosing regimen. The package provides an efficient, versatile way to specify dosing scenarios and to perform simulation with variability with minimal custom coding. Models can be directly translated to Rshiny applications to facilitate interactive, real-time evaluation/iteration on simulation scenarios.
Language: English
Open Access status: gold
Estimated APC paid: $4,140
OpenAlex ID: W2180605142
FWCI: 3.212
Cites: 14
Cited by: 106
Related to: 10