FgNoxR, a regulatory subunit of NADPH oxidases, is required for female fertility and pathogenicity inFusarium graminearum
Year: 2015
Type: article
Abstract: Fusarium graminearum is a filamentous fungal pathogen that causes wheat Fusarium head blight. In this study, we identified FgNoxR, a regulatory subunit of NADPH oxidases (Nox) in F. graminearum, and found that it plays an important role in the pathogenicity of F. graminearum. FgNoxR is localized on punctate structures throughout the cytoplasm in aerial hyphae while these structures tend to accumulate at or near the plasma membrane, septa and hyphal tips in germinated conidia. Deletion of the FgNOXR gene results in reduced conidiation and germination. Importantly, sexual development is totally abolished in the FgNOXR deletion mutant. In addition, the disease lesion of FgNOXR deletion mutant is limited to the inoculated spikelets of wheat heads. Finally, FgNoxR interacts with FgRac1 and FgNoxA, and all three proteins are required for female fertility. Taken together, our data indicate that FgNoxR contributes to conidiation, sexual reproduction and pathogenesis in F. graminearum.
Source: FEMS Microbiology Letters
Authors: Chengkang Zhang, Yahong Lin, Jianqiang Wang, Yang Wang, Miaoping Chen, Justice Norvienyeku, Guangpu Li, Wenying Yu, Zonghua Wang
Institution: Fujian Agriculture and Forestry University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
SDG: Zero hunger
Open Access status: bronze
Award: G1375197330
OpenAlex ID: W2181292419