Inflammatory response to a high-force eccentric exercise protocol in oral contraceptive users and non-users
Year: 2008
Type: dissertation
Abstract: Researchers have demonstrated that oral contraceptive users have elevated serum C-reactive protein (CRP) levels. However, it is unclear whether or not CRP is elevated in response to inflammation. Results of preliminary studies indicate that individuals with elevated CRP exhibit diminished release of interleukin-6 (IL-6), an inflammatory mediator with anti-inflammatory properties. Low IL-6 may cause less control of inflammation and a resultant elevation of CRP. The inflammatory response was compared between female oral contraceptive (OC) users and non-OC users because of the known elevation of CRP in OC users. A high-force eccentric exercise protocol was used to induce muscle damage to the biceps brachii via 45 repetitions of the elbow flexors of the non-dominant limb. Blood was collected pre-exercise and at 4-, 8-, 12-, 24-, 48-, 96-, and 120-h post-exercise for analysis of muscle damage and inflammatory markers.
Author: Christine E. Kasper
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2182780547