Hypolipidemic Effect of Extra Virgin Olive Oil in Diabetic Rats
Year: 2012
Type: article
Abstract: Background: To evaluate the effect of monounsaturatedfatty acid and phenolic compounds enriched extra virginolive oil on correction of dyslipidemia in diabetic rats.Methods: In this randomized control trial eighty albinorats of Sprague-Dawley strain weighing 200-250 gramswere randomly divided into two groups of 40 rats each.Rats were made diabetic by injecting streptozotocin.Group 1 and Group 2 were given normal rodent diet andextra virgin olive oil supplemented diet respectively for 06weeks. At the end of experimentation lipid profile wasmeasured.Results: There was significant increase of high densitylipoprotein and significant decrease of serum totalcholesterol, serum triglycerides and low densitylipoprotein of Group II rats when it was compared withGroup I (control).Conclusion: Extra virgin olive oil can significantlyimprove lipid profile in diabetic rats.
Authors: Muhammad Javad Yousaf, Abdul Khaliq Naveed, Tausif Ahmed Rajput, Shakir Khan, Zahid Azeem
Institution: Army Medical College
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $35
OpenAlex ID: W2183615319