Work

Regulation of Cryptococcus neoformans Capsule Size Is Mediated at the Polymer Level

Year: 2007

Type: article

Abstract: The fungal pathogen Cryptococcus neoformans regulates its polysaccharide capsule depending on environmental stimuli. To investigate whether capsule polymers change under different growth conditions, we analyzed shed capsules at physiological concentrations without physical perturbation. Our results indicate that regulation of capsule size is mediated at the level of individual polysaccharide molecules.

Source: Eukaryotic Cell

DOI: 10.1128/ec.00437-07

Authors: Aki Yoneda, Tamara L. Doering

Institution: Washington University in St. Louis

Language: English

Topic: Fungal Infections and Studies

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

Open Access status: diamond

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Polysaccharide capsule export in the fungal pathogen Cryptococcus neoformans, GLYCAN BIOSYNTHESIS IN CRYPTOCOCCUS NEOFORMANS