Oculopharyngodistal myopathy in three unrelated Korean patients: Early distal limb weakness is a characteristic fi nding in oculopharyngodistal myopathy
Year: 2011
Type: article
Study design: Case Report
Abstract: Objectives: To determine the clinical characteristics of Korean patients with sporadic oculopharyngodistal\nmyopathy. Methods: Three consecutive unrelated Korean patients with sporadic oculopharyngodistal\nmyopathy participated in this study. Stepwise approaches were performed including careful clinical\nexamination, electrophysiological study, pathology evaluation and genetic study. The literature on\noculopharyngodistal myopathy was reviewed. Results: Clinically, our patients showed consistent\nfeatures of initial distal limb weakness with variable ophthalmoplegia, bulbar weakness or proximal\nweakness. All the patients showed rimmed vacuoles and myopathic changes.\nConclusion: Through the literature review and this study, we believe that initial distal limb weakness\nis a characteristic fi nding in patients with oculopharyngodistal myopathy in some ethnic groups.
Authors: Sun‐Young Kim, Jeong-Keun Lim, Changhoon Lee, Dae‐Seong Kim
Institution: Pusan National University
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2184157980