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Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin

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Year: 2015
Type: review
Source: Current Opinion in Genetics & Development
DOI: 10.1016/j.gde.2015.08.001
Authors: Daniel E Bauer, Stuart H Orkin
Institutions: Boston Children's Hospital, Harvard University, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Howard Hughes Medical Institute
Language: English

Topic: Hemoglobinopathies and Related Disorders
Subfield: Genetics (clinical)
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: A CENTER OF MOLECULAR DEVELOPMENTAL HEMATOPOIESIS, DEVELOPMENTAL BIOLOGY OF HUMAN ERYTHROPOIESIS, Molecular Analysis of Normal and Thalassemic DNA, G5138542659, Epigenetic regulation of BCL11A in the hemoglobin switch, Translational and clinical studies targeting y-globin modulation, G9000124058
OpenAlex ID: W2185201235
FWCI: 1.763
Cites: 75
Cited by: 147
Related to: 10
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