Work

Cloud-scale RNA-sequencing differential expression analysis with Myrna

Year: 2010

Type: article

Abstract: As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the analysis of publicly available data sets and assess the goodness of fit of standard statistical models. Myrna is available from http://bowtie-bio.sf.net/myrna.

Source: Genome biology

DOI: 10.1186/gb-2010-11-8-r83

Authors: Ben Langmead, Kasper D Hansen, Jeffrey T Leek

Institution: Johns Hopkins University

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $5,490