Modeling slow wave activity patterns across the scalp
Year: 2007
Type: book-chapter
Abstract: In models of sleep regulation, timing of sleep is linked to the temporal dynamics of slowwave activity (SWA, EEG spectral power in ~0.75–4.5 Hz range) in the cortical NREM sleep EEG. In the original two process model of sleep regulation, SWA was used as an indicator of sleep debt. The time constant of the SWA decrease over consecutive NREM–REM sleep cycles was used to estimate the time course of process S during sleep. Later, SWA expression was assumed to reflect the decay rate of process S rather than sleep debt directly. A detailed model describing the overnight SWA pattern with its intrusions of REM sleep and waking was made by Achermann, refining the description of the changes in SWA and process S over the night. In this model, process S and SWA are coupled by a ‘gain constant’, quantifying the efficiency of SWA in dissipating S. The time course of SWA during sleep after sleep deprivation varies between cortical locations, suggesting that local differences in process S exist. In this study, we estimate local differences of S regulation by fitting ‘gain constants’ for 26 locations on the scalp. We observed higher frontal ‘gain constants’, suggesting that indeed regulation of S has local differences.
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2186013240