Xerostomia Management for Pediatric Oncology Patients with Lactoperoxidase Included Oral Health Care Products
Year: 2013
Type: article
Abstract: Aim: Evaluating the efficacy of lactoperoxidase included oral care products for xerostomia in children with cancer undergoing chemotherapy and / or radiotherapy and to present an easy to follow oral care protocol.Design: The study subjects consisted of twenty one pediatric cancer patients (mean age of 11,3±) with either leukemia or lymphoma used lactoperoxidase-system-containing mouth rinse (Biotene ® ) combined with (Biotene ® ) gel or (Biotene ® ) chewing gum for 3 weeks.Unstimulated saliva samples were collected at the base line and 4 weeks after the usage of the products.They were analyzed for selected biochemical factors and subjective symptoms as intra-oral dryness (xerostomia), eating ability and oral discomfort were graded by visual analogue scale.Results: No major changes occurred in the level of saliva Thiocyanite and Peroxidase activity, but there was a increase in salivary pH and also salivary flow rate was notably higher in groups using Lactoperoxidase products.Changes related to buffering capacity of saliva were also recorded.Conclusion: There is no clearly effective treatment for xerostomia but we have observed in our practice that the use of non-immunologic antimicrobial agents relieves subjective oral symptoms in most xerostomic pediatric patients.
Source: Dentistry
Author: Tanboga Durmus B
Institutions: Istanbul University, Marmara University
Language: English
Subfield: General Dentistry
Field: Dentistry
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2186412394