Work

Allele Frequency and Genotype Distribution of 9 SNPs in the Kazakh Population

Year: 2014

Type: article

Abstract: The VKORC1 gene on chromosome 16 is one of the major genes associated with effective doses of coumarin anticoagulants.Many mutations are associated with a deficiency in this enzyme.The allelic variant VKORC1 c.-1639G>A determines up to 30% of the variability in warfarin dosage [3][4][5][6][7][8].

Source: Journal of Pharmacogenomics & Pharmacoproteomics

DOI: 10.4172/2153-0645.1000129

Author: Aliya A Romanova

Institutions: National Center for Biotechnology, National Academy of Education named after Y. Altynsarin

Language: English

Topic: Pharmacogenetics and Drug Metabolism

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Ministry of Education and Science of the Republic of Kazakhstan