A Review-Emerging Use of Nano-Based Carriers in Diagnosis and Treatment of Cancer-Novel Approaches
Year: 2015
Type: article
Abstract: Despite intensive research efforts, cancer remains one of the leading causes of death in the world. Many new methods and techniques have been developed in order to improve diagnosis and treatment, often promising in the beginning, but with limited results during the course of their application. In recent years, there has been an unprecedented expansion in the field of nanomedicine with the development of new nanoparticles for the diagnosis and treatment of cancer. Nanoparticles have unique biological properties given their small size and large surface area-to-volume ratio, which allows them to bind, absorb, and carry compounds such as small molecule drugs, DNA, RNA, proteins, and probes with high efficiency. Their tunable size, shape, and surface characteristics also enable them to have high stability, high carrier capacity, the ability to incorporate both hydrophilic and hydrophobic substances and compatibility with different administration routes, thereby making them highly attractive in many aspects of oncology. The expansion of novel nanoparticles for drug delivery is an exciting and challenging research filed, in particular for the delivery of emerging cancer therapies, including small interference RNA (siRNA) and microRNA (miRNAs)-based molecules.
Authors: Yaqub Khan, Brijesh Kumar Saroj, Maryada Roy, Irfan Aziz
Institution: Mangalayatan University
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W1965254596