Work

Multiple recombinant dengue type 1 viruses in an isolate from a dengue patient

Year: 2007

Type: article

Abstract: Between 2000 and 2004, dengue virus type 1 (DENV-1) genotypes I and II from Asia were introduced into the Pacific region and co-circulated in some localities. Envelope protein gene sequences of DENV-1 from 12 patients infected on the island of New Caledonia were obtained, five of which carried genotype I viruses and six, genotype II viruses. One patient harboured a mixed infection, containing viruses assigned to both genotypes I and II, as well as a number of inter-genotypic recombinants. This is the first report of a population of dengue viruses isolated from a patient containing both parental and recombinant viruses.

Source: Journal of General Virology

DOI: 10.1099/vir.0.83122-0

Authors: John Aaskov, Katie Buzacott, Emma Field, Kym Lowry, Alain Berlioz-Arthaud, Edward C. Holmes