Work

Congenital hyperinsulinism presenting with different clinical, biochemical and molecular genetic spectra

Year: 2013

Type: article

Abstract: Congenital hyperinsulinism (CHI) is a common cause of hypoglycemia in infants. We report three cases of CHI with differing clinical, biochemical, and molecular genetic spectra. One patient was unresponsive to medical treatment and died after subtotal pancreatectomy because of complications due to the surgery. Two patients have been followed successfully with medical treatment. Early diagnosis and appropriate treatment of CHI are essential to prevent morbidity and mortality.

Source: The Turkish Journal of Pediatrics

DOI: 10.24953/turkjped.2013.1560

Authors: Enver Şimşek, Çiğdem Binay, Sarah E. Flanagan, Sian Ellard, Khalid Hussain, Sare Kabukçuoğlu

Institutions: Eskişehir Osmangazi University, University of Exeter, Great Ormond Street Hospital, University College London

Language: English

Topic: Pancreatic function and diabetes

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: University of Exeter