Work

Diastolic and Systolic Heart Failure Are Distinct Phenotypes Within the Heart Failure Spectrum

Year: 2011

Type: article

Abstract: Heart failure (HF) is a major worldwide public healthproblem. One in 5 people aged 40 years in the United States will develop HF during his or her lifetime,1 and HF remains the leading cause for hospitalization among the elderly.2 Although age- and sex-specific HF incidence is not increasing,3 overall HF survival has improved, and the number of people aged65 years is increasing rapidly. Thus, the absolute number of patients with HF will continue to increase. Half of the patients with HF have a preserved ejection fraction (HFpEF), and the remainder display reduced ejection fraction (HFrEF).4–6 The proportion of patients with normal ejection fraction (EF) is increasing steadily because of increased incidence and/or increasing physician recognition of the syn-drome.4 Resource utilization associated with HF is high in both the inpatient and outpatient settings, regardless of EF. Response by De Keulenaer and

Source: Circulation

DOI: 10.1161/circulationaha.110.954388

Authors: Barry A. Borlaug, Margaret M. Redfield

Institution: Mayo Clinic

Language: English

Topic: Heart Failure Treatment and Management

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Heart, Lung, and Blood Institute