Year: 1965
Type: article
Abstract: Zajac, Ihor (Hahnemann Medical College, Philadelphia, Pa.), and Richard L. Crowell. Location and regeneration of enterovirus receptors of HeLa cells. J. Bacteriol. 89:1097-1100. 1965.-Treatment of live HeLa cells with chymotrypsin or trypsin completely inactivated the viral receptors for coxsackievirus B3 and poliovirus T1, respectively. Enzyme-treated cells regained their enterovirus receptor activity after incubation in culture medium. The existence of intracellular receptors for virus could not be demonstrated when live HeLa cells were treated with enzyme prior to disruption and fractionation. These results suggested that receptors for enteroviruses are limited to the cell surface.
Source: Journal of Bacteriology
Authors: Ihor Zajac, Richard L. Crowell
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1537477126