Work

Current Understandings of Molecular Biology of Echinococcus multilocularis, a Pathogen for Alveolar Echinococcosis in Humans- a Narrative Review Article.

Year: 2015

Type: review

Abstract: BACKGROUND: Echinococcus multilocularis is a tiny tapeworm, responsible for 0.3~0.5 million alveolar echinococcosis in humans. METHODS: We searched relevant papers published between 1981 and 2013 based on the database sources such as PubMed and Google scholar, and collected and integrated the data for analysis. RESULTS: The parasite is able to use host-originated molecules to modulate its development and has complex signalling pathways than expected previously. E. multilocularis utilizes many types of alternative splicing approaches to generate transcript isoforms. Recently, the genome of E. multilocularis has been deciphered. CONCLUSION: These data will give us a profound understanding of biology of E. multilocularis, which will promote the use as a model to study helminths.

Source: PubMed Central

Authors: Xiaoqiang Wang, Juntao Ding, Xiaola Guo, Yadong Zheng

Institutions: Lanzhou Jiaotong University, Xinjiang University, Lanzhou Veterinary Research Institute

Language: English

Topic: Parasitic infections in humans and animals

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2188593593

FWCI: 0.17

Cites: 45

Cited by: 4

Related to: 10