Askaridiozisli Yavru Köpeklerde Topikal Selamektin Uygulamasının Doza Bağlı Etkinliği
Year: 2006
Type: article
Abstract: SUMMARY This study evaluated the effects of different doses of Selamectin’s topical application on puppies with ascaridiosis. The study involved 12 puppies up to 40-60 days old. Animals were divided into two equal groups; dogs in the group I were treated with topical selamectin at the dose of 6 mg/kg, body weight (bw), the others (Group II) were treated with topical selamectin at the dose of 12 mg/kg, bw. Ascaride eggs were counted before treatment (day 0) and after treatment on the day 7 and 14 using the Mc Master technique. The clinical, hematological, and biochemical findings of day 0, 7, and 14 were also examined. Total red blood cell (RBC) of puppies in group II (p<0.05) and hematocrite value in both groups significantly increased on the 14 th day compared prior to the treatment (p<0.01); leukocyte numbers decreased in the group II on the 7 th (p<0.05) and 14 th (p<0.01) days compared prior to the treatment. Differential leukocyte count revealed a significant decrease in the proportion of eosinophil after treatment in both groups on the 14 th day (p<0.01). Total protein concentrations increased in both groups of treatment regimen on day 7 (p<0.05) and 14 (p<0.01). But, albumin and globulin concentrations increased only in the group II of treatment regimen on day 14 (p<0.05). Egg counts per gram of faeces in both group decreased after treatment but this was more obvious in group II. As a result, it is determined that a considerable improvement was achieved in a shorter time in group treated with 12 mg/kg of selamectin when clinical, haematological, biochemical parameters and egg counts were taken into consideration.
Language: Turkish
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2188723613