Year: 2015
Type: article
Abstract: In the early 1990’s several groups were searching for the molecular basis of the signal transduction triggered by the engagement of plasma membrane receptors. The laboratories of Darnell, Kerr and Stark were first to identify proteins, which acted as intermediaries in interferon (IFN) signaling, known as the signal transducer and activator of transcription (STAT). At the same time, the work of Pellegrini’s, Ihle’s and Carter-Su’s groups demonstrated that non-receptor tyrosine kinases, previously described by
Source: Oncoscience
Authors: Raul Rabadan, Giorgio Inghirami
Institution: Weill Cornell Medicine
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2189346095