Constructing Realistic Engrams: Poststimulus Activity of Hippocampus and Dorsal Striatum Predicts Subsequent Episodic Memory
Year: 2011
Type: article
Abstract: Encoding of real-life episodic memory commonly involves integration of information as the episode unfolds. Offline processing immediately following event offset is expected to play a role in encoding the episode into memory. In this study, we examined whether distinct human brain activity time-locked to the offset of short narrative audiovisual episodes could predict subsequent memory for the gist of the episodes. We found that a set of brain regions, most prominently the bilateral hippocampus and the bilateral caudate nucleus, exhibit memory-predictive activity time-locked to the stimulus offset. We propose that offline activity in these regions reflects registration to memory of integrated episodes.
Source: Journal of Neuroscience
Authors: A. Ben-Yakov, Y. Dudai
Institution: Weizmann Institute of Science
Language: English
Topic: Memory and Neural Mechanisms
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2008440029