Work

Identification of the Gene for the Yeast Ribonucleotide Reductase Small Subunit and Its Inducibility by Methyl Methanesulfonate

Year: 1987

Type: article

Abstract: We have identified, cloned, and sequenced the gene for the small subunit of ribonucleotide diphosphate reductase of Saccharomyces cerevisiae. The protein and its transcript are induced about 10-fold by the alkylating agent methyl methanesulfonate, a result which suggests that the gene is induced by DNA damage.

Source: Molecular and Cellular Biology

DOI: 10.1128/mcb.7.10.3673

Authors: H K Hurd, C W Roberts, J W Roberts

Institution: Cornell University

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: G4809649946, G5128583541, G9000055732