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Importancia de la sintasas del óxido nítrico en el metabolismo del hueso

Year: 2012
Type: article
Abstract: In the last 20 years, nitric oxide NO• has proven to be a universal molecular messenger essential in multiple physiological functions of diversely tissues, including bone. In bone, NO• is produced by nitric oxide synthase (NOS) which exists in three isomorphs: endothelial, neuronal and inducible nitric oxide synthase NOSe, NOSn, and NOSi, respectively, each one with specific functions. This review describes the importance of each NOS isomorph for bone tissue, as well as the controversy surrounding the action of NO• in bone produced endogenously by these isomorphs and organic NO• donors.
Language: Spanish
Open Access status: diamond
OpenAlex ID: W2193484822
FWCI:
Cites: 77
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Related to: 10