Work

First-in-human study of PF-00299804, a small molecule irreversible panHER inhibitor in patients with advanced cancer: Update on safety and pharmacokinetics and initial report on pharmacodynamic responses and clinical benefit.

Year: 2007

Type: article

Study design: Clinical Trial

Source: Molecular Cancer Therapeutics

Authors: D. Ross Camidge, Carolyn D. Britten, Jan H.M. Schellens, Fan Guo, R Milham, Sabine Eckhardt, Steven Wong, David S. Boss, Joan Lucca, Pasi A. Jänne

Institutions: University of California, Los Angeles, Ronald Reagan UCLA Medical Center, UCLA Medical Center, The Netherlands Cancer Institute, Dana-Farber Cancer Institute, University of Colorado Denver

Language: English

Topic: HER2/EGFR in Cancer Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2197932199

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