Work

The sinonasal bacterial microbiome in health and disease

Year: 2015

Type: article

Abstract: PURPOSE OF REVIEW: The development of culture-independent bacterial DNA sequencing techniques and integration into research practice has led to a burgeoning interest in the microbiome and its relevance to human health and disease. Introduction into the study of chronic rhinosinusitis in the past few years has shaped current thinking on the role of bacteria in the disease process. RECENT FINDINGS: Rich and diverse populations of bacteria inhabit the sinonasal cavity at all times. Decreased bacterial richness and diversity may be associated with disease state and outcomes. SUMMARY: Although there is much to be explored, the sinus microbiome appears to have potentially promising roles in many aspects of sinus health and disease.

Source: Current Opinion in Otolaryngology & Head & Neck Surgery

DOI: 10.1097/moo.0000000000000221

Authors: Vijay R. Ramakrishnan, Leah J. Hauser, Daniel N. Frank

Institutions: University of Colorado Anschutz, University of Colorado Denver

Language: English

Topic: Sinusitis and nasal conditions

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Deafness and Other Communication Disorders