Year: 2008
Type: article
Abstract: Objectives: The root of trigeminal nerve (Cr5) and its trigeminal ganglion (TG) are located in the middle cranial fossa which has important anatomical relations. We thought that anatomical and histological studies of Cr5 and TG would increase surgical success carried out in this region. In this study, we aimed to investigate the morphological features and variations of Cr5 and the associated structures. Material and Methods: A total of 40 intracranial portions of Cr5 's obtained from 20 forensic autopsy cadavers were studied and tissue samples were taken. The intracranial course of Cr5 was examined carefully, and possible types of variations were investigated. Then, tissue samples taken were stained with Hematoxylin&Eosin and Mallory's anilin blue collagen staining histologically. Results: Mean length of Cr5's was found as 25.32±2.90 mm and TG's width as 13.5±1.2 mm. In four cases, motor root was located inferomedially to the sensorial root. Cr5's were located near to vascular structures particularly. Total number of bundles was found as 71.75±8.20. Diameters of the fibers of the big fascicule and the small fascicule were found as 9.11±0.98 µm and 3.17±0.26 µm respectively. Satellite cells were observed more in TG. Collagen/neuron ratios was calculated as 2/5 and 1/6 in TG and Cr5 respectively. Conclusion: This study might contribute to enlighten the demography of Cr5 in our country, clinical sciences, surgical success and some related disorders. In addition, variable collagen/neuron ratios found in TG and Cr5 (as can vary in diabetes and multiple sclerosis) also further suggest that more investigation is needed.©2008, Firat University, Medical Faculty.
Source: DergiPark (Istanbul University)
Language: Turkish
Subfield: Anatomy
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2199709767