Work

Stem cell potential of the mammalian gonad

Year: 2009

Type: article

Abstract: Stem cells have enormous potential for therapeutic application because of their ability to self-renew and differentiate into different cell types. Gonads, which consist of somatic cells and germ cells, are the only organs capable of transmitting genetic materials to the offspring. Germ-line stem cells and somatic stem cells have been found in the testis; however, the presence of stem cells in the ovary remains controversial. In this review, we discuss studies focusing on whether stem cell properties are present in the different cell types of male and female gonads and their implications on stem cell research.

Source: Frontiers in Bioscience-Elite

DOI: 10.2741/e47

Author: Humphrey Hung-Chang Yao

Institution: University of Illinois Urbana-Champaign

Language: English

Topic: Reproductive Biology and Fertility

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Environmental Health Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development