Mechanisms underlying subthreshold and suprathreshold responses in dorsal cochlear nucleus cartwheel cells.
Year: 2005
Type: article
Abstract: Cartwheel cells (CWCs) are a group of interneurons in the dorsal cochlear nucleus (DCN).Unlike other DCN neurons, which respond to stimuli with simple spikes, or trains of individual action potentials, CWCs respond to suprathreshold stimuli with complex spikes, rapid bursts of action potentials superimposed on a slow depolarization, or a combination of simple and complex spikes.In vitro whole-cell current clamp recordings from young rats (P11 -P15) show that CWCs respond to brief suprathreshold stimuli with complex spikes or simple spikes followed by afterdepolarizations (ADPs); and to subthreshold stimuli with subthreshold depolarizations (SDPs).Although complex spikes iii List of Tables 1 Comparison of Na+ mediated APs obtained from CWCs in adult (> 1 month old) guinea pig and in P11 -P16 rat DCN.124 x
Author: Mingjie Tong
Institution: University of Toledo
Language: English
Subfield: Sensory Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2207096220