Work

Rational design of α-helical tandem repeat proteins with closed architectures

Year: 2015

Type: article

Source: Nature

DOI: 10.1038/nature16191

Authors: Lindsey Doyle, Jazmine Hallinan, Jill Bolduc, Fabio Parmeggiani, David Baker, Barry L. Stoddard, Philip Bradley

Institutions: Fred Hutch Cancer Center, University of Washington, Howard Hughes Medical Institute

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Howard Hughes Medical Institute, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, National Institutes of Health, National Institute of General Medical Sciences

Awards: FHCRC High-Performance Computing Cluster, Prediction and Design of Nucleic Acid Recognition by Repeat Proteins, Determination of the basis of ligand binding via engineering and crystallography, Structure, function and engineering of nuclease catalysts, G454222003, Design of sequence specific endonucleases for gene therapy

OpenAlex ID: W2209424705

FWCI: 6.799

Cites: 46

Cited by: 126

Related to: 10