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Fluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg2+ to the second metal binding site

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Year: 2015
Type: article
Source: Biochimica et Biophysica Acta (BBA) - General Subjects
DOI: 10.1016/j.bbagen.2015.12.019
Authors: Lisa M. Oppegard, Heidi A. Schwanz, Tyrell R. Towle, Robert J. Kerns, Hiroshi Hiasa
Institutions: University of Minnesota, University of Iowa
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: American Foundation for Pharmaceutical Education, National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases
Awards: Predoctoral Training Program in Biotechnology, Antibacterial Agents that Restrict the Emergence of Resistance
OpenAlex ID: W2210614062
FWCI: 0.579
Cites: 48
Cited by: 11
Related to: 10
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