Work

MDSCs enhance tumor cell proliferation in a caspase-1 related inflammasome cytokines dependent way

Year: 2015

Type: article

Abstract: Meeting abstracts Myeloid-derived-suppression cells (MDSCs) are believed to be an important immune evasion mechanism by suppressing T cells. We investigated whether MDSCs have direct T cell independent pro-carcinogenic effect on tumor cells. We sorted the monocytic CD14+/CD11b+/HLA-DRlow MDSCs from

Source: Journal for ImmunoTherapy of Cancer

DOI: 10.1186/2051-1426-3-s2-p317

Authors: Qi Zeng, Jesse Qualliotine, Richard Blosser, Drew Pardoll, Young Kim

Institution: Johns Hopkins University

Language: English

Topic: Immune cells in cancer

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,490