Quantitative Electrocardiography for Prediction of Postoperative Atrial Fibrillation After Cardiac Surgery
Year: 2010
Type: article
Study design: Observational Study
Abstract: Background: Postoperative atrial fibrillation (POAF) after cardiac surgery is a common marker of poor outcomes and can be reduced with medical prophylaxis.Methods: Quantitative ECG measurements and clinical patient characteristics predictive of POAF were identified with stepwise logistic regression and 500-fold bagging in a cohort of patients undergoing coronary artery bypass and/or valve surgery.Results: 4762 (35%) of 13416 patients developed POAF.Independent ECG predictors were a less negative P wave amplitude in lead aVR (OR 1.46, CI 1.32-1.61)and a larger P wave amplitude in lead V1 (OR 1.25, CI 1.16-1.36,per 0.1 mV).Greater age and left atrial volume, prior episodes of atrial arrhythmias, and valvular surgery were risk factors; black race and hypothyroidism were protective from POAF.Conclusion: P wave amplitude in lead aVR and V1 are important predictors of postoperative atrial fibrillation after cardiac surgery and in combination with clinical predictors can guide prophylactic medication use.
Author: Florian Rader
Institution: Case Western Reserve University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Cleveland Clinic
OpenAlex ID: W2212192787