Noninvasive Brain Stimulation in Pediatric Attention-Deficit Hyperactivity Disorder (ADHD)
Year: 2015
Type: article
Abstract: Attention-deficit hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in the pediatric population. The clinical management of ADHD is currently limited by a lack of reliable diagnostic biomarkers and inadequate therapy for a minority of patients who do not respond to standard pharmacotherapy. There is optimism that noninvasive brain stimulation may help to address these limitations. Transcranial magnetic stimulation and transcranial direct current stimulation are 2 methods of noninvasive brain stimulation that modulate cortical excitability and brain network activity. Transcranial magnetic stimulation can be used diagnostically to probe cortical neurophysiology, whereas daily use of repetitive transcranial magnetic stimulation or transcranial direct current stimulation can induce long-lasting and potentially therapeutic changes in targeted networks. In this review, we highlight research showing the potential diagnostic and therapeutic applications of transcranial magnetic stimulation and transcranial direct current stimulation in pediatric ADHD. We also discuss the safety and ethics of using these tools in the pediatric population.
Source: Journal of Child Neurology
Authors: Belen Rubio, Aaron D. Boes, Simon Laganiere, Alexander Rotenberg, Danique Jeurissen, Alvaro Pascual-Leone
Institutions: Hospital Universitario de Canarias, Beth Israel Deaconess Medical Center, Harvard University, Massachusetts General Hospital, Berenson Allen Center for Noninvasive Brain Stimulation, Boston Children's Hospital, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Awards: G1087526407, G1336442044, Cortical connectivity, physiology, and response to stimulation in human epilepsy, Role of functional brain connectivity on efficacy of TMS for depression, Harvard Clinical and Translational Science Center (UL1), Cortical plasticity in type II diabetes mellitus, Transcranial Direct Current Stimulation and Robotic Training in Chronic Stroke, Mapping progressive loss of intracortical inhibition by TMS and EEG in posttraumatic epileptogenesis, Transcranial Stimulation in Spino-Cerebellar Ataxia, Neuroscience Resident Research Program
OpenAlex ID: W2213277078