Work

Adhesins Involved in Attachment to Abiotic Surfaces by Gram-Negative Bacteria

Year: 2015

Type: review

Abstract: During the first step of biofilm formation, initial attachment is dictated by physicochemical and electrostatic interactions between the surface and the bacterial envelope. Depending on the nature of these interactions, attachment can be transient or permanent. To achieve irreversible attachment, bacterial cells have developed a series of surface adhesins promoting specific or nonspecific adhesion under various environmental conditions. This article reviews the recent advances in our understanding of the secretion, assembly, and regulation of the bacterial adhesins during biofilm formation, with a particular emphasis on the fimbrial, nonfimbrial, and discrete polysaccharide adhesins in Gram-negative bacteria.

Source: Microbiology Spectrum

DOI: 10.1128/microbiolspec.mb-0018-2015

Authors: Cécile Berne, Adrien Ducret, Gail G. Hardy, Yves V. Brun

Institutions: Indiana University Bloomington, Indiana University

Language: English

Topic: Bacterial biofilms and quorum sensing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Synthesis and properties of a bacterial bioadhesive