Year: 2011
Type: article
Abstract: Phylogenetic reconstruction using DNA and protein sequences has allowed the reconstruction of evolutionary histories encompassing all life. We present and discuss a means to incorporate much of this rich narrative into a single model that acknowledges the discrete evolutionary units that constitute the organism. Briefly, this Rooted Net of Life genome phylogeny is constructed around an initial, well resolved and rooted tree scaffold inferred from a supermatrix of combined ribosomal genes. Extant sampled ribosomes form the leaves of the tree scaffold. These leaves, but not necessarily the deeper parts of the scaffold, can be considered to represent a genome or pan-genome, and to be associated with members of other gene families within that sequenced (pan)genome. Unrooted phylogenies of gene families containing four or more members are reconstructed and superimposed over the scaffold. Initially, reticulations are formed where incongruities between topologies exist. Given sufficient evidence, edges may then be differentiated as those representing vertical lines of inheritance within lineages and those representing horizontal genetic transfers or endosymbioses between lineages.
Source: Biology Direct
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,890
Awards: Horizontal gene transfer and among phyla relationships, "GENOME-BASED INVESTIGATIONS INTO THE NATURE OF THE COMMON ANCESTOR OF THE THERMOTOGALES"THIS PROJEC, EXPLORATION OF SEQUENCE SPACE AND THE EVOLUTION OF THE GENETIC CODEPROTEINS CONSIST OF LINEAR SEQUENCES OF AMINO ACIDS. THESE SEQUENCES CAN BE THOUG
OpenAlex ID: W2163827204
