Increase in Macroglobulin Antibodies of Mouse and Pig Following Injection of Bacterial Lipopolysaccharide.
Year: 1964
Type: article
Abstract: A single intraperitoneal injection of 30 mg. of lipopolysaccharide into a pig gave rise to a rapid evanescent increase in opsonic activity towards Salmonella typhimurium C5. This increase was due to antibodies which were shown by density gradient centrifugation and DEAE chromatography to be β(2)M macroglobulins and to be indistinguishable from the `natural' antibodies present in normal pig serum. The macroglobulin concentration and the opsonic activity were shown to increase for several days but were returning to normal by the 15th day.
Source: PubMed Central
Authors: D ROWLEY, K J TURNER
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2220772208