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Rate-dependent force, intracellular calcium, and action potential voltage alternans are modulated by sarcomere length and heart failure induced-remodeling of thin filament regulation in human heart failure: A myocyte modeling study

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Year: 2015
Type: article
Source: Progress in Biophysics and Molecular Biology
DOI: 10.1016/j.pbiomolbio.2015.12.012
Authors: Melanie A. Zile, Natalia A. Trayanova
Institution: Johns Hopkins University
Language: English

Topic: Cardiac electrophysiology and arrhythmias
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Foundation, Foundation for the National Institutes of Health, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Center for Chronic Disease Prevention and Health Promotion
Awards: Exploration of Arrhythmogenic Triggers and Substrates in Heart Failure, Virtual Electrophysiology Laboratory, Resynchronizing the Failing Heart: Insights from a Multiscale Cardiac Model, Biomedical Engineering Training Program, CDI Type-II: Collaborative Research: From Ion Channels to Blood Flow and Heart Sounds: A New Paradigm in Cyber-Enabled Multiphysical Analysis of Heart Function, G7730036676, G814569518, G983294019
OpenAlex ID: W2221253263
FWCI: 2.179
Cites: 74
Cited by: 17
Related to: 10
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