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EBV-Positive Grey Zone Lymphoma in an HIV Infected Man from Kampala, Uganda: Case Report

Year: 2015

Type: article

Abstract: AIM: We describe the clinical, histopathological and immunophenotypic characteristics of an HIV-infected adult man on antiretroviral therapy who presented with an EBV-positive grey zone lymphoma. CASE PRESENTATION: hybridization. The patient improved on modified CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone) therapy. DISCUSSION: The tumour had features intermediate between mediastinal large B cell lymphoma and classical Hodgkin lymphoma. CONCLUSION: We present a case of EBV-positive grey zone lymphoma in an HIV-infected man on HAART therapy diagnosed and treated in a resource constrained medical setting. The histological features are unusual and represent a low incidence lymphoma that is recognized by mixed features reminiscent of Hodgkin's lymphoma and mediastinal large B-cell lymphoma.

Source: International Journal of Medical and Pharmaceutical Case Reports

DOI: 10.9734/ijmpcr/2015/13625

Authors: L. Tumwine, J. Orem, L. Ayers

Institutions: Makerere University, Uganda Cancer Institute, The Ohio State University Wexner Medical Center, The Ohio State University

Language: English

Topic: Viral-associated cancers and disorders

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Cancer Institute