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Direct activation of STING in the tumor microenvironment partially overcomes immune tolerance in neu-N transgenic mice

Year: 2015
Type: article
Abstract: Meeting abstracts STING signaling induces interferon-β production by intratumoral dendritic cells (DCs), driving T cell priming within the tumor microenvironment. However, the impact of antigen-specific tolerance on this process is not well studied. We therefore examined the efficacy of in situ
DOI: 10.1186/2051-1426-3-s2-p356
Authors: Jeremy Foote, James M Leatherman, Todd D Amstrong, Laureen Ojalvo, David Kanne, Elizabeth M Jaffee, Tom Dubensky, Leisha Emens
Language: English
Subfield: Immunology
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2230125040
FWCI:
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Related to: 10