A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
Year: 2015
Type: article
Study design: Observational Study
Source: Nature Genetics
DOI: 10.1038/ng.3448
Authors: Lars G Fritsche, Wilmar Igl, Jessica N Cooke Bailey, Felix Grassmann, Sebanti Sengupta, Jennifer L Bragg-Gresham, Kathryn P Burdon, Scott J Hebbring, Cindy Wen, Mathias Gorski, Ivana K Kim, David Cho, Donald Zack, Eric Souied, Hendrik P N Scholl, Elisa Bala, Kristine E Lee, David J Hunter, Rebecca J Sardell, Paul Mitchell, Joanna E Merriam, Valentina Cipriani, Joshua D Hoffman, Tina Schick, Yara T E Lechanteur, Robyn H Guymer, Matthew P Johnson, Yingda Jiang, Chloe M Stanton, Gabriëlle H S Buitendijk, Xiaowei Zhan, Alan M Kwong, Alexis Boleda, Matthew Brooks, Linn Gieser, Rinki Ratnapriya, Kari E Branham, Johanna R Foerster, John R Heckenlively, Mohammad I Othman, Brendan J Vote, Helena Hai Liang, Emmanuelle Souzeau, Ian L McAllister, Timothy Isaacs, Janette Hall, Stewart Lake, David A Mackey, Ian J Constable, Jamie E Craig, Terrie E Kitchner, Zhenglin Yang, Zhiguang Su, Hongrong Luo, Daniel Chen, Hong Ouyang, Ken Flagg, Danni Lin, Guanping Mao, Henry Ferreyra, Klaus Stark, Claudia N von Strachwitz, Armin Wolf, Caroline Brandl, Guenther Rudolph, Matthias Olden, Margaux A Morrison, Denise J Morgan, Matthew Schu, Jeeyun Ahn, Giuliana Silvestri, Evangelia E Tsironi, Kyu Hyung Park, Lindsay A Farrer, Anton Orlin, Alexander Brucker, Mingyao Li, Christine A Curcio, Saddek Mohand-Saïd, José-Alain Sahel, Isabelle Audo, Mustapha Benchaboune, Angela J Cree, Christina A Rennie, Srinivas V Goverdhan, Michelle Grunin, Shira Hagbi-Levi, Peter Campochiaro, Nicholas Katsanis, Frank G Holz, Frédéric Blond, Hélène Blanché, Jean-François Deleuze, Robert P Igo, Barbara Truitt, Neal S Peachey, Stacy M Meuer, Chelsea E Myers, Emily L Moore, Ronald Klein, Michael A Hauser, Eric A Postel, Monique D Courtenay, Stephen G Schwartz, Jaclyn L Kovach, William K Scott, Gerald Liew, Ava G Tan, Bamini Gopinath, John C Merriam, R Theodore Smith, Jane C Khan, Humma Shahid, Anthony T Moore, J Allie McGrath, Reneé Laux, Milam A Brantley, Anita Agarwal, Lebriz Ersoy, Albert Caramoy, Thomas Langmann, Nicole T M Saksens, Eiko K de Jong, Carel B Hoyng, Melinda S Cain, Andrea J Richardson, Tammy M Martin, John Blangero, Daniel E Weeks, Bal Dhillon, Cornelia M van Duijn, Kimberly F Doheny, Jane Romm, Caroline C W Klaver, Caroline Hayward, Michael B Gorin, Michael L Klein, Paul N Baird, Anneke I den Hollander, Sascha Fauser, John R W Yates, Rando Allikmets, Jie Jin Wang, Debra A Schaumberg, Barbara E K Klein, Stephanie A Hagstrom, Itay Chowers, Andrew J Lotery, Thierry Léveillard, Kang Zhang, Murray H Brilliant, Alex W Hewitt, Anand Swaroop, Emily Y Chew, Margaret A Pericak-Vance, Margaret DeAngelis, Dwight Stambolian, Jonathan L Haines, Sudha K Iyengar, Bernhard H F Weber, Gonçalo R Abecasis, Iris M Heid
Institutions: University of Michigan, University of Regensburg, Case Western Reserve University, Michigan Medicine, University of Tasmania, Marshfield Clinic Research Foundation, Marshfield Clinic Research Institute, University of California San Diego, VA San Diego Healthcare System, Massachusetts Eye and Ear Infirmary, Harvard University, University of Pennsylvania, Institut de la Vision, Johns Hopkins University, Johns Hopkins Medicine, Université Pierre-et-Marie-Curie, Université Paris-Est Créteil, Hôpitaux Universitaires Henri-Mondor, Hôpital Intercommunal de Créteil, University of Bonn, Louis Stokes Cleveland VA Medical Center, University of Wisconsin–Madison, University of Miami, The University of Sydney, Westmead Institute for Medical Research, Columbia University, Moorfields Eye Hospital, University College London, Vanderbilt University Medical Center, University Hospital Cologne, Radboud University Medical Center, The University of Melbourne, The Royal Victorian Eye & Ear Hospital, Centre for Eye Research Australia, The University of Texas Rio Grande Valley, University of Pittsburgh, Institute of Genetics and Cancer, MRC Human Genetics Unit, Medical Research Council, University of Edinburgh, Erasmus MC, The University of Texas Southwestern Medical Center, National Institutes of Health, National Eye Institute, Flinders University, Flinders Medical Centre, Lions Eye Institute, The University of Western Australia, University of Electronic Science and Technology of China, Chinese Academy of Sciences, Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy, Ludwig-Maximilians-Universität München, University Hospital Regensburg, University of Utah, Boston University, Seoul National University, Seoul Metropolitan Government, SNUH SMG-SNU Boramae Medical Center, Queen's University Belfast, University of Thessaly, Seoul National University Bundang Hospital, Weill Cornell Medicine, University of Alabama at Birmingham, Centre National de la Recherche Scientifique, Inserm, Centre hospitalier national d'ophtalmologie des Quinze-Vingts, Institut de France, Fondation Ophtalmologique Adolphe de Rothschild, Académie des sciences, University of Southampton, University Hospital Southampton NHS Foundation Trust, Hadassah Medical Center, Duke University, Fondation Jean Dausset-CEPH, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Genoscope, Cleveland Clinic, Duke Medical Center, New York University, University of Cambridge, Royal Perth Hospital, National Health Service, Cambridge University Hospitals NHS Foundation Trust, University of California, San Francisco, University of California San Francisco Medical Center, Vanderbilt University, Oregon Health & Science University, University of California, Los Angeles, Radboud University Nijmegen, Brigham and Women's Hospital
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: U.S. Department of Veterans Affairs, University of Michigan, National Institute for Health and Care Research, Universität Regensburg, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Eye Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, U.S. National Library of Medicine, National Center for Advancing Translational Sciences
Awards: G1119622688, Genetic Studies of Dementia in the Amish, G1442900148, NIHR Senior Investigator Award, G1696649581, G1702040024, Genetic Epidemiology of Age-Related Macular Degeneration in the Older Order Amish, G2509621741, G2648776141, G2686194219, Development and Application of Phenome-wide Scan of Heritability (PheSH), G2920646418, G3127079477, G3226771441, G4193739534, NIHR Senior Investigator Award, G4407350458, G4539512084, G4838978803, G5694410176, Institutional Clinical and Translational Science Award, G6710079994, G6904192639, G721603795, G781942980
OpenAlex ID: W2233221674